Backup running backs often play a crucial yet understated role in fantasy football leagues. Identifying the right handcuffs can be instrumental in determining the difference between winning a championship and failing to make the playoffs. This task can be somewhat complex, particularly in today's NFL, where the lines between starting and backup roles frequently blur due to the prevalent use of platoon systems. Additionally, the landscape can shift rapidly, as injuries and performance issues often trigger changes in the depth chart, influencing fantasy outcomes significantly.

With this in mind, a comprehensive analysis of each NFL team's handcuff running back is presented, ranking them predominantly based on their inherent standalone value and potential upside should they be thrust into a starting role. The evaluation of these primary backups has been informed by training camp reports, snap count data, and past utilization trends. For instance, Kendre Miller, once regarded as a promising handcuff, has seen his stock diminish over the years reflecting a lack of significant output since entering the league. With only 454 yards and two touchdowns from scrimmage across 14 games, and failing to establish himself effectively, he should only be rostered in the league's deepest formats.

On a brighter note for the Cincinnati Bengals, sixth-round rookie Chase Brown presents an opportunity that could make him a valuable asset. Despite his ability to potentially outperform veteran Samaje Perine, the anticipated volume of work this season seems likely to favor Brown's teammate, Joe Mixon, who is expected to maintain the bulk of the responsibilities in the backfield. The uncertainty surrounding the depth chart could leave Brooks with limited relevance unless significant injuries impact the ranks. Similarly, for the Green Bay Packers, Tyler Goodson's performance in the previous season leaves much to be desired, further complicated by injuries that contributed to a rocky start to his career. Thus, the depth behind established starters like Josh Jacobs and others remains a significant factor in their prospects for 2025.