Selecting backup running backs can be a crucial decision in fantasy football leagues, as identifying the right handcuffs can significantly impact a team's chances of success. The lines between starting and backup running backs are increasingly blurring in the current NFL landscape, with many teams employing platoon approaches. Given the unpredictable nature of injuries and performance inconsistencies, the depth chart can shift rapidly, influencing fantasy outcomes. This article explores a ranked analysis of handcuff running backs from each NFL team, taking into account player potential, training camp reports, snap count data, and previous season trends.

For the New Orleans Saints, Kendre Miller was once a promising option, but his performance has not met expectations. Since entering the league, Miller has accumulated only 454 yards and two touchdowns from scrimmage across 14 games. His injury history has clouded his future, making him a candidate for deep league consideration but not much more. On the other hand, the Cincinnati Bengals made a notable pick in sixth-rounder Chase Brown, a player who may take on primary duties barring injuries to established backs. Meanwhile, Green Bay Packers' running back2024 draft pick Lloyd has yet to establish himself, struggling with injuries and limited touches, while the Philadelphia Eagles' Saquon Barkley leads a backfield where backups like Will Shipley can only expect minimal contributions.

The Indianapolis Colts' Johnathan Taylor has returned to form, complicating the opportunities for rookie DJ Giddens, who could be a strong option if Taylor faces injury challenges. The Las Vegas Raiders, during the 2025 draft, secured Ashton Jeanty, a generational talent expected to take over the backfield; Raheem Mostert serves as the complementary veteran. The Los Angeles Rams look to explore more versatility within their offensive strategies, potentially creating opportunities for Kyren Williams and potentially setting up Jahmyr Gibbs alongside David Montgomery for more successful pairing. With the likes of Derrick Henry solidifying his place in the Ravens' rushing prowess and the Kansas City Chiefs welcoming back Kareem Hunt, the backup situations across the league remain dynamic and essential to monitor for fantasy landscapes.