The Moneyline MLB 30 in '30 series takes a forward-looking approach, anticipating the performance of the top 30 players at each position by the year 2030. This installment focuses on second basemen, a position that traditionally sees many shortstop prospects transitioning down the defensive spectrum due to various factors, including the emergence of established shortstop talents. An example of this is Jackson Holliday, who was drafted as a shortstop but later moved to second base at the major league level.

In predicting the future top talents at second base, evaluations considered both offensive and defensive capabilities, although the ultimate ranking relied heavily on subjective projection. Before presenting the projected list, it is worth recognizing several current stars likely to either retire or shift positions before the onset of the 2030 season, including notable players like Ozzie Albies of the Atlanta Braves and Jose Altuve of the Houston Astros, among others.

The rankings commence with Termarr Johnson of the Pittsburgh Pirates at number 30. After being drafted fourth overall in 2022, Johnson is still developing but possesses a highly regarded hit tool. He is followed by Max Muncy from the Las Vegas Athletics, who had a promising start at Triple-A after being selected in the 2021 draft. Others who made the list include Juan Brito of the Cleveland Guardians and Nico Hoerner of the Chicago Cubs, both of whom exhibit strong offensive and defensive attributes. Among the higher-ranking players projected for 2030 are established talents like Gleyber Torres, Jazz Chisholm Jr., and future stars still making their way through the minor leagues.