Each MLB season introduces a new cohort of young talent transitioning from prospects to rookies. The 2024 season saw notable names such as Paul Skenes, Jackson Merrill, and Shōta Imanaga making headlines. As the 2025 season approaches, attention turns to the next wave of prospects ready to make their mark. This article highlights the most MLB-ready prospect from each MLB organization, emphasizing those players who have yet to exceed 130 at-bats, 50 innings pitched, or 45 days on the active roster, thus retaining their prospect status.

For the Baltimore Orioles, first/third baseman Coby Mayo (Age: 23) stands out. After a strong season at Triple-A, where he boasted a .926 OPS, 23 doubles, 22 home runs, and 67 RBI in 89 games, Mayo’s performance suggests he has little left to prove in the minors. He may have struggled in his initial big league stint, going 4-for-41 with 22 strikeouts, but his potential replacement for Ryan Mountcastle makes him a player to watch. The Boston Red Sox's Roman Anthony (Age: 20) could very well enter the season as the top prospect in baseball after an impressive .291/.396/.498 tally with 54 extra-base hits and 21 steals in 119 games between Double-A and Triple-A. Anthony's youth and potential merit attention amidst a crowded Red Sox outfield.

In New York, Jasson Dominguez (Age: 21), a top outfield prospect for the Yankees, is poised for a starting role after an injury-marred season, where he produced a .314/.376/.504 line in 58 games. Meanwhile, the Tampa Bay Rays' Ian Seymour (Age: 26) offers a strong case for a rotation spot or a role as a bulk reliever after a standout 2024 campaign. For the Toronto Blue Jays, Will Wagner (Age: 26) has proven his worth with a .305 batting average, making a compelling argument for a place in the lineup. Each of these players exemplifies the potential impact newcomers can have in the MLB landscape as they aim to solidify their roles within their respective teams.