Major League Baseball (MLB) teams commemorated Lou Gehrig Day on Sunday by wearing special No. 4 patches and wristbands, a poignant tribute to the legendary player. The fifth annual Lou Gehrig Day is slated for June 2, 2025, and teams not competing on Monday participated in this homage a day early, as noted by MLB. The No. 4 patches are uniquely designed to reflect the font and colors of the New York Yankees, celebrating Gehrig's remarkable 17-year tenure with the organization.

Athletes participating in the games also had the opportunity to wear red '4-ALS' wristbands. This initiative is part of MLB's broader effort to raise awareness for Amyotrophic Lateral Sclerosis (ALS), which is commonly referred to as Lou Gehrig's disease. Among those touched by this cause is Colorado Rockies outfielder Sam Hilliard, whose father, Dr. Jim Hilliard, passed away from ALS in 2021. Hilliard's mother, Tamara Hilliard, played a significant role in establishing Lou Gehrig Day as an annual event, as reported by Thomas Harding from MLB.com. Sam Hilliard further marked the occasion by donning a custom pair of cleats during the 2025 events.

Moreover, Sunday marked the centenary of a remarkable milestone: June 1, 1925, when Gehrig commenced his legendary streak of 2,130 consecutive games played. Since 2021, MLB has honored this anniversary with patches and wristbands commemorating Gehrig's legacy. In addition to these tributes, this year MLB is set to present a tribute video in ballparks during games on Sunday and Monday. Nicknamed 'the Iron Horse,' Gehrig showcased his extraordinary talent over 2,164 games played for the Yankees and secured six World Series titles before his retirement in 1939, a retirement that was shadowed by the diagnosis of what would become known as ALS.