Following the Philadelphia Eagles' commanding victory over the Kansas City Chiefs in Super Bowl LIX, attention has shifted to the frontrunners for the next championship, which is set to take place in Santa Clara, California. The Eagles emerged as the early favorites for Super Bowl 60, opening with +550 odds after their decisive 40-22 win over the back-to-back champions. Quarterback Jalen Hurts showcased an outstanding performance, completing 221 passing yards, two touchdown throws, and a rushing touchdown. Veteran running back Saquon Barkley also contributed with 57 rushing yards. This emphatic win eliminated the Chiefs from contention for a historic three-peat, positioning the Eagles as the clear leaders heading into the off-season.

The Kansas City Chiefs, despite their setback in the Super Bowl, opened at +700 odds, reflecting a strong chance of reclaiming the title next season. They are tied for the second-best odds alongside the Buffalo Bills and the Baltimore Ravens, each also listed at +700. The Bills, powered by MVP quarterback Josh Allen, concluded the previous season with a notable 13-4 record, topping the AFC East before facing a narrow 32-29 defeat to the Chiefs in the AFC Championship game. Allen, who amassed 3,731 passing yards and 28 touchdowns with an impressive quarterback rating of 77.3, aims for his first Super Bowl appearance next year. Moreover, the Ravens, finishing at 12-5 before their playoff exit against the Bills, remain a formidable opponent in the AFC with two-time MVP Lamar Jackson leading the charge, having recorded 41 touchdowns and 4,172 passing yards during the season.

In a surprising turnaround, the Washington Commanders have vaulted from a dismal 4-13 record to a commendable 12-5 finish, elevating their Super Bowl aspirations with +1,900 odds, ranking them eighth overall. Meanwhile, the Detroit Lions, despite last having reached the Super Bowl in 1957, are garnering attention among the top contenders with +900 odds. The San Francisco 49ers, last season's runner-up in Super Bowl LVIII, are positioned at +1,500 odds, while the Cincinnati Bengals, recent Super Bowl finalists, are not far behind with +1,800 odds. Lastly, the Tennessee Titans and Cleveland Browns find themselves at the bottom of the odds spectrum, each listed at +20,000 following a subpar season ending in a 3-14 record.